Therapeutic irradiation may produce a variety of adverse side effects on the central and the peripheral nervous systems. These adverse effects are divided into two main groups ; transient and permanent. Four major clinical syndromes have been
described
in relation to permanent radiation in fury of the nervous system : encephalopathy, cranial neuropathy, myelopathy, and peripheral neuropathy.. Among Among them, delayed encephalopathy represents the major hazard in CNS irradiation. The
characterisitic
MR imaging pattern of radiation induced delayed necrotizing leukoencephalopathy is symmetric, high-signal foci on T2WI in the periventricular white matter.
We report a case of suspected post-irradiation leukoencephalopathy showed progressive mental change, quadriparesis, and urinary incontinence with characteristic MR findings who had taken therapeutic irradiatio 12 months ago.
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